RTSA                    R version of Trial Sequential Analysis. Used
                        for designing and analysing sequential
                        meta-analyses.
boundaries              Boundaries for group sequential designs
coronary                Dataset of trials investigating the intensity
                        of statin therapy on the risk of myocardial
                        infarction or coronary death
eds                     Dataset of trials investigating the effect of
                        carer on early supported discharge services
inference               Inference calculations for sequential
                        meta-analysis
metaanalysis            Fixed-effect or random-effects meta-analysis
minTrial                Minimum number of trials needed for a specific
                        level of power
perioOxy                Dataset of RCTs investigating the effect of 80%
                        perioperative oxygen vs. 30 -35% perioperative
                        oxygen on surgical site infection.
plot.RTSA               Plot RTSA object. Returns the R version of the
                        original TSA plot.
plot.boundaries         Plot of boundaries for group sequential designs
plot.metaanalysis       Forestplot for metaanalysis object.
ris                     Calculate required sample and trials size.
