CI.Rsq.measure          Functions to generate the confidence interval
                        of the Rsq measure using nonparametric
                        bootstrap.
Rsq.measure             Function to calculate the Rsq function as a
                        total mediation effect size measure (Gaussian
                        outcome only). If method='iSIS', a two-step
                        procedure is performed, where the first step
                        filters the non-mediators based on part of the
                        data and the second step calculates the point
                        estimates for Rsq using random-effect models on
                        the remaining data. If method='ALL', Rsq is
                        calculated based on all subjects and variables.
example                 Example dataset
