Package: grantham
Type: Package
Title: Calculate the 'Grantham' Distance
Version: 0.1.1
Authors@R: c(
    person(given = "Ramiro", family = "Magno",
      email = "ramiro.magno@gmail.com",
      role = c("aut", "cre"),
      comment = c(ORCID = "0000-0001-5226-3441")),
    person(given = "Isabel", family = "Duarte",
      email = "iduarte.scientist@gmail.com",
      role = "aut",
      comment = c(ORCID = "0000-0003-0060-2936")),
    person(given = "Ana-Teresa", family = "Maia",
      email = "maia.anateresa@gmail.com", role = "aut", 
      comment = c(ORCID = "0000-0002-0454-9207")),
    person("CINTESIS",
    role = c("cph", "fnd"))
    )
Description: A minimal set of routines to calculate the 'Grantham' distance
    <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to
    provide a proxy for the evolutionary distance between two amino acids
    based on three key chemical properties: composition, polarity and
    molecular volume. In turn, evolutionary distance is used as a proxy for
    the impact of missense mutations. The higher the distance, the more
    deleterious the substitution is expected to be.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.2
Depends: R (>= 2.10)
Imports: tibble, magrittr, vctrs, dplyr, tidyr, rlang, stringr
URL: https://maialab.org/grantham/, https://github.com/maialab/grantham
BugReports: https://github.com/maialab/grantham/issues
Suggests: spelling
Language: en-US
NeedsCompilation: no
Packaged: 2022-01-07 02:12:22 UTC; rmagno
Author: Ramiro Magno [aut, cre] (<https://orcid.org/0000-0001-5226-3441>),
  Isabel Duarte [aut] (<https://orcid.org/0000-0003-0060-2936>),
  Ana-Teresa Maia [aut] (<https://orcid.org/0000-0002-0454-9207>),
  CINTESIS [cph, fnd]
Maintainer: Ramiro Magno <ramiro.magno@gmail.com>
Repository: CRAN
Date/Publication: 2022-01-07 03:20:02 UTC
Built: R 4.0.5; ; 2022-01-25 03:11:01 UTC; unix
